Zycortal Suspension 4ml

Zycortal Suspension (Desoxycorticosterone Pivalate) is an injectable for use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s Disease). 

Desoxycorticosterone is a corticosteroid with primarily mineralocorticoid activity, similar to aldosterone. In the kidney, desoxycorticosterone causes sodium and chloride ion retention, and hydrogen and potassium ion excretion, creating an osmotic gradient that promotes water absorption from the renal tubules. This increases extracellular fluid volume, leading to blood volume expansion, improved venous return to the heart, and increased cardiac output.

Dispensed in:

25 mg/ml, 4 ml vial

For Use in:

Dogs only

Side Effects:

It has been demonstrated that Desoxycorticosterone Pivalate Injectable Suspension is well tolerated with a low incidence of side effects. In a small percentage of treated dogs, depression, excessive thirst and urination, digestive, skin and coat changes, weakness, and injection site reactions (pain, abscesses) may occur. Some of these effects may resolve with adjustments in dose or interval or concomitant glucocorticoid administration. Do not use in pregnant dogs or in dogs that are suffering from congestive heart disease, severe renal disease, or edema.

Precautions:

Do not use Zycortal Suspension in dogs that have previously had a hypersensitivity reaction to desoxycorticosterone pivalate. CAUTIONS: Any dog presenting with severe hypovolemia, dehydration, pre-renal azotemia and inadequate tissue perfusion (“Addisonian crisis”) must be rehydrated with intravenous fluid (saline) therapy before starting treatment with Zycortal Suspension. Avoid inadvertent intravenous injection which may have an adverse effect on the dog. The effectiveness of Zycortal Suspension may be reduced if potassium-sparing diuretics, such as spironolactone, are administered concurrently. Use Zycortal Suspension with caution in dogs with congestive heart disease, edema, severe renal disease or primary hepatic failure. Desoxycorticosterone pivalate may cause polyuria, polydipsia, increased blood volume, edema and cardiac enlargement. Excessive weight gain may indicate fluid retention secondary to sodium retention. The safety of desoxycorticosterone pivalate has not been established in breeding, pregnant and lactating dogs and dogs less than 6 months of age.

Manufacturer: Dechra

In case of overdose Contact your nearest emergency animal hospital

Store between 15-30°C. Do not freeze. Use within 120 days of first puncture.

Please Note: 

This prescription product or therapeutic food is fulfilled by Pet’s Choice Pharmacy, Inc. A licensed pharmacy in all states, excluding North Carolina. Pet’s Choice is actively working with North Carolina Board of Pharmacy and expect to be licensed to fill prescriptions in 2017. We can only ship to US states. 

To order prescription products or therapeutic foods must have an existing, valid veterinarian-client-patient relationship.  Prescription requests are subject to a Drug Utilization Review by a licensed pharmacist for patient safety.

All prescription products (excluding therapeutic food) are FDA approved, or EPA licensed, to be sold in the US.

Prescription products cannot be returned.